Is it safe to take benadryl and ibuprofen together

Applies to: Mucinex DM (dextromethorphan / guaifenesin) and Benadryl (diphenhydramine) Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor ...

Is it safe to take benadryl and ibuprofen together. Do you know how gun safe work? Learn how gun safes work at HowStuffWorks. Advertisement Most responsible gun owners know the choice to own a deadly weapon comes with the obligation...

Trazodone may cause dry mouth. For temporary relief, use sugarless gum or candy, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth ...

The short answer: It depends on the drugs in question. But in the case of gabapentin and Tylenol (acetaminophen), you can take them both together. In fact, many folks do. While both medications ...Jan 6, 2023 · Diphenhydramine can cause decreased reaction times and dizziness. In older people with other medical problems or physical impairments, this may lead to falls or accidents, especially while getting up to urinate at night. The potential for bone fractures is a notable concern. Moving a gun safe can require special equipment. We break down the best gun safe movers in your area. Expert Advice On Improving Your Home Videos Latest View All Guides Latest View...Piroxicam: learn about side effects, dosage, special precautions, and more on MedlinePlus People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) s...Answer. Benadryl (diphenhydramine), Ambien (zolpidem), and melatonin are not recommended to be taken together due to additive sedation and additive CNS depression. The resulting side effects could be dangerous. Two or more of these medications should only be taken together under the recommendation and supervision of your doctor.Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation, while Benadryl is an antihistamine used to alleviate allergy symptoms. …

Answer. Benadryl (diphenhydramine), Ambien (zolpidem), and melatonin are not recommended to be taken together due to additive sedation and additive CNS depression. The resulting side effects could be dangerous. Two or more of these medications should only be taken together under the recommendation and supervision …Diphenhydramine and ibuprofen combination is used to relieve trouble sleeping caused by minor aches and pains. It also helps you fall asleep and stay asleep. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used in this combination to relieve inflammation, swelling, and pain.Benadryl is short-acting and Claritin can generally be given 4 to 8 hours after. Hi there and thanks for reaching out! Both Benadryl (diphenhydramine) and Claritin (loratadine) are antihistamines and are …The health service has explained that it is safe to take ibuprofen with painkillers like paracetamol and codeine. However, Dr T Shaw has urged that you should stagger the doses. The doctor ...Specializes in Pediatrics. Yes: There is no interaction between the two medicines. Be sure you know the individual doses of each. Both can be given every 6 hours as needed. Also, some Benadryl (diphenhydramine) preparations have ibuprofen already in it, so make sure you don't double dose with one of these. Read ingredient list carefully on each ...And while both acetaminophen and ibuprofen are typically safe, Dr. Horwitz says that if you have kidney, digestive, bleeding or liver problems, you need to be careful with taking …Apr 1, 2024 · Diphenhydramine. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Ibuprofen. Studies in women suggest that this medication poses minimal risk to the infant when used ... Before you try it, make sure you’re not already taking a drug (like OTC cold meds) that contains acetaminophen or ibuprofen since taking too much of either drug can be dangerous, says Dr. Alan ...

Key points. Benadryl and Allegra are both antihistamines, and generally should not be taken together consistently. However, there are times when it may be okay to take both during the course of one day if recommended by your doctor. In most cases, it would not be recommended to take Benadryl ( diphenhydramine) and Allegra ( fexofenadine) together.Applies to: Vicks DayQuil Severe Cold & Flu (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) and Benadryl (diphenhydramine) Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also ...Apr 1, 2024 · Each tablet contains 38 milligrams (mg) diphenhydramine and 200 mg ibuprofen. Do not take more than 2 tablets in 24 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. Ibuprofen/diphenhydramine is generally safe to take, but it's not the best choice for everyone. This medication might not be appropriate for you if you have certain conditions, such as a history of serious side effects from other pain relievers or allergy medications, breathing problems, stomach or stomach bleed problems, kidney problems, heart problems, or a history of stroke.In conclusion, taking ibuprofen and Benadryl together is generally safe under the supervision of your healthcare professional. However, it is essential to …Indomethacin: learn about side effects, dosage, special precautions, and more on MedlinePlus People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such...

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Combining Benadryl and Nyquil can cause increased drowsiness, as both medications contain antihistamines known to cause sedation. It’s essential to avoid driving or operating machinery when experiencing drowsiness due to medication use. Benadryl and Nyquil should NOT be taken together. Doing so can result in increased sedation and fall …No adverse interactions have been found between Benadryl Allergy and ibuprofen. As a matter of fact, Ibuprofen and Diphenhydramine the active ingredient in Benadryl are combined in …Answer. Hi there and thanks for reaching out! Yes, Benadryl ( diphenhydramine) may be safely taken with Tylenol ( acetaminophen) as there is no drug …Descriptions. Tramadol and acetaminophen combination is used to relieve acute pain severe enough to require an opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. When used together, the combination provides better pain relief than either medicine used alone.It is safe to take ibuprofen and Paracetamol (acetaminophen) together, says NHS Choices. Ibuprofen and acetaminophen are two different types of painkillers, and no interactions app...

A total of 446 drugs are known to interact with Benadryl Children's Allergy . Benadryl children's allergy is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl children's allergy is used to treat the following conditions:Mucinex (guaifenesin) and Sudafed (pseudoephedrine) can safely be taken together. In fact, there are a variety of medications that combine both active ingredients. These two meds are used to treat ...Key takeaways: Hydroxyzine (Vistaril) is a medication used for allergies, itching, and anxiety. It interacts with several medications and alcohol. Opioid pain medications and other antihistamines, such as diphenhydramine (Benadryl), interact with hydroxyzine. Combining them can cause severe drowsiness and raise the chance of …While both Benadryl and propranolol can be used together, caution is advised in regard to the potential for additive adverse reactions such as sedation and dizziness. Propranolol is known to cause sedation and orthostatic hypotension (a drop in blood pressure while standing), which can cause dizziness. Benadryl causes …Taking prednisone and an NSAID at the same time raises the risk of stomach-related side effects, including bleeding and ulcers. It’s best to avoid taking NSAIDs and prednisone together for this reason. Talk to your HCP about taking acetaminophen (Tylenol) for pain instead of an NSAID. Acetaminophen is easier on the stomach.I’m not generally a fan of TikTok—it’s the place teenagers go to take part in stupid, dangerous shit like the “Skull Breaker Challenge” or the “Benadryl Challenge.” It’s also the ...Lower-cost generic is available. Ratings & Reviews. Benadryl has an average rating of 7.3 out of 10 from a total of 78 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. Ibuprofen has an average rating of 7.3 out of 10 from a total of 240 ratings on Drugs.com. 65% of reviewers reported a ... Wondering whether it’s safe to take Benadryl and Ibuprofen together? Well, you’re not alone. Many people have questioned the compatibility of these two medications. So, let’s dive in and explore the risks involved. Firstly, it is generally considered safe to take Benadryl (an antihistamine) and Ibuprofen (a nonsteroidal anti-inflammatory ... The short answer: It depends on the drugs in question. But in the case of gabapentin and Tylenol (acetaminophen), you can take them both together. In fact, many folks do. While both medications ...Diphenhydramine (Benadryl) is an over-the-counter antihistamine commonly used to treat allergy symptoms. It’s also used as a sleep aid and found in many cough …busPIRone diphenhydrAMINE. Applies to: buspirone and Benadryl (diphenhydramine) Using busPIRone together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Is it safe to mix ibuprofen and Benadryl? This article explores the potential risks, benefits, and precautions of taking these two medications together.

Ibuprofen (Advil) received an overall rating of 8 out of 10 stars from 22 reviews. See what others have said about Ibuprofen (Advil), including the effectiveness, ease of use and s...

Yes, for most individuals, it is safe to take Tylenol PM (which contains acetaminophen and diphenhydramine) and losartan (brand name Cozaar) together. However, it is important to note two things regarding this combination: Both can cause sedation and lightheadedness. This is especially true of diphenhydramine in general and …Combining Benadryl and Ibuprofen may increase the risk of certain side effects, such as drowsiness, dizziness, and dry mouth. Both medications can cause sedation, and taking them together can intensify this effect. It is important to note that driving or operating heavy machinery while under the influence of these medications can be dangerous.This effect can occur when combining gabapentin and Benadryl (diphenhydramine) or gabapentin and Unisom (doxylamine). Some common combinations of gabapentin and OTC medications for allergy relief and pain relief include: Gabapentin and Tylenol (acetaminophen) Gabapentin and Advil (ibuprofen) Is it safe to take Cymbalta …Potential benefits of taking Benadryl and DayQuil together. Combining Benadryl and DayQuil may provide potential benefits in managing various symptoms associated with colds, flu, or allergies. Benadryl can help relieve allergy symptoms like sneezing, runny nose, and itching. DayQuil, on the other hand, can alleviate symptoms like fever, cough ...Applies to: Mucinex DM (dextromethorphan / guaifenesin) and Benadryl (diphenhydramine) Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor ...Before you try it, make sure you’re not already taking a drug (like OTC cold meds) that contains acetaminophen or ibuprofen since taking too much of either drug can be dangerous, says Dr. Alan ...Question: Are stable-value funds a safe investment? —Rexford, Syracuse, New York Answer: That depends on what you mean by safe. Stable-value funds, which are available… By c...Nonsteroidal anti-inflammatory drugs (NSAIDs) treat pain and fever. They’re commonly found over the counter (OTC) and with a prescription. Examples include aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn). They’re go-to choices for a bothersome headache or a short spell of muscle pain, but combining them with …Lower-cost generic is available. Ratings & Reviews. Benadryl has an average rating of 7.3 out of 10 from a total of 78 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. Ibuprofen has an average rating of 7.3 out of 10 from a total of 240 ratings on Drugs.com. 65% of reviewers reported a ...

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Yes, you can safely take acetaminophen and ibuprofen together. And it may surprise you that taking these two medications together actually works better to relieve pain than taking them separately. Studies have shown that ibuprofen (Advil, Motrin) and acetaminophen (Tylenol) together work well to relieve certain types of pain, and …Here are a few key points to know about taking aspirin and ibuprofen at the same time. If you take ibuprofen occasionally, there's not much risk that it will interfere with the effect of low-dose aspirin. If you need just one dose of ibuprofen, take it 8 hours before or 30 minutes after taking a regular, non-coated, and not extended-release ...Summary. Acetaminophen (Tylenol) and ibuprofen (Advil) are two of the most common pain-relieving medications and fever reducers. Ibuprofen is a pain reliever and an anti-inflammatory drug, whereas acetaminophen acts on pain. Though both are safe for most when taken as directed, adverse effects can arise with acetaminophen and …Melatonin is a hormone that regulates the body's circadian rhythm (the sleep-wake cycle). It's also available as a dietary supplement. Like Benadryl, it's often used for sleep disturbances like insomnia (trouble falling or staying asleep). There's some controversy over whether these two medicines are safe to take together.Medications. All of the following medications can be safely given together: Antibiotics including amoxicillin, cefdinir/Omnicef ®, amoxicillin-clavulanate/Augmentin ®, azithromycin/Zithromax ®, cephalexin/Keflex ®, and trimethoprim-sulfamethoxazole/Bactrim ® . Antihistamines including Benadryl ® /diphenhydramine, Claritin ® /loratidine ...liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common side effects of acetaminophen and diphenhydramine may include: dry mouth, nose, or throat. This is not a complete list of side effects and others may occur.A safe house works for both good guys and bad guys, keeping them hidden and secure. There's a safe house mentioned in the Bible, and safe houses during WWII. Advertisement You're o...Answer. Benadryl (diphenhydramine), Ambien (zolpidem), and melatonin are not recommended to be taken together due to additive sedation and additive CNS depression. The resulting side effects could be dangerous. Two or more of these medications should only be taken together under the recommendation and supervision of your doctor.Taking them together can raise the risk of kidney problems. You should avoid this interaction if possible. If you need to take cyclosporine and ibuprofen, your healthcare provider will likely check your cyclosporine levels more often. They’ll likely also recommend taking the lowest ibuprofen dosage possible and staying well-hydrated. 10. …You’ve probably seen this warning on medicines you’ve taken. The danger is real. Mixing alcohol with certain medications can cause nausea and vomiting, headaches, drowsiness, fainting, or loss of coordination. It also can put you at risk for internal bleeding, heart problems, and difficulties in breathing. In addition to these dangers, alcohol can make a … ….

If you’re unsure about whether it’s safe for you to take Ibuprofen and Benadryl together, seek medical advice. Combining Ibuprofen and Benadryl may increase sedation and pose a higher risk of gastrointestinal side effects. To ensure your safety and well-being, consult a healthcare professional before taking these medications together.Key takeaways: Hydroxyzine (Vistaril) is a medication used for allergies, itching, and anxiety. It interacts with several medications and alcohol. Opioid pain medications and other antihistamines, such as diphenhydramine (Benadryl), interact with hydroxyzine. Combining them can cause severe drowsiness and raise the chance of …This one is relatively straightforward. Yes, ibuprofen is safe to take with diphenhydramine (generic for Benadryl). There is no known interaction between the two …Answer. Aspirin and Benadryl have no known drug interactions. They are considered to be safe to take together. It is important to note however, that if you take aspirin for cardio-protection (e.g. low dose aspirin daily), Benadryl has been associated with adverse cardiac effects, such as: Adverse cardiac effects on Benadryl are rare, but …Blood-thinning drugs with NSAIDs. Your odds for a dangerous bleed could go up. NSAIDs (nonsteroidal anti-inflammatory drugs) are pain relievers like ibuprofen or naproxen.Before you try it, make sure you’re not already taking a drug (like OTC cold meds) that contains acetaminophen or ibuprofen since taking too much of either drug can be dangerous, says Dr. Alan ...If you take any of these medications, your doctor may need to lower your dose of them temporarily or monitor you closely for potential side effects once you start taking amoxicillin. Tylenol, Ibuprofen (Advil) and Aspirin. Common painkillers like Tylenol, ibuprofen and aspirin also have potential side effects that overlap with those of ...Yes, you can safely take acetaminophen and ibuprofen together. And it may surprise you that taking these two medications together actually works better to relieve pain than taking them separately. Studies have shown that ibuprofen (Advil, Motrin) and acetaminophen (Tylenol) together work well to relieve certain types of pain, and …Metoprolol is a generic prescription medication approved by the U.S. Food and Drug Administration (FDA). It is classified as a beta-blocker (in the same drug class as medications such as propranolol and atenolol) and works by relaxing blood vessels and slowing the heart rate to lower blood pressure and improve blood flow. Metoprolol may …Both medications contain diphenhydramine as their active ingredient. Taking Nyquil and Benadryl together can potentially increase the diphenhydramine level in your system beyond what is considered safe. Excessive amounts of diphenhydramine can lead to side effects such as drowsiness, dizziness, blurred vision, dry mouth, and constipation. Is it safe to take benadryl and ibuprofen together, Answer. Yes, oral antihistamines can be used in conjunction with nasal antihistamines, although current data suggests that the combination of the two is no more effective than using a nasal antihistamine as the sole treatment. Below, we discuss the data available in regard to whether or not there is benefit in combining an oral antihistamine ..., Descriptions. Ibuprofen and oxycodone combination is used to relieve acute, moderate to severe pain. Ibuprofen is a nonsteroidal antiinflammatory drug (NSAID) that is used to relieve inflammation, swelling, and pain. Oxycodone is a narcotic analgesic that acts in the central nervous system to relieve pain. If oxycodone is used for a long time ..., Benadryl (diphenhydramine) Children's Motrin (ibuprofen) Edit list (add/remove drugs) Consumer; ... Ask your doctor before using ibuprofen together with ethanol. Do not drink alcohol while taking ibuprofen. ... you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use ..., Applies to: Vicks DayQuil Severe Cold & Flu (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) and Benadryl (diphenhydramine) Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also ..., Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or ..., Yes, you can. Benadryl and Tylenol have not been shown to interact with each other. They’re generally safe to take together, so long as you stick to the dosage …, The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative ..., Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce mild to moderate pain, inflammation, and fever. Ibuprofen works by blocking an enzyme that makes prostaglandin (a hormone-like substance that participates in a variety of body functions), which results in lower levels of prostaglandins in the body., Benadryl. A total of 446 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis. Allergies., It’s safe for most people to take allergy medications that are in different classes. For example, nasal steroids, such as Flonase (fluticasone propionate), and oral decongestants, such as Sudafed (pseudoephedrine), can be taken together. However, you shouldn’t combine multiple oral antihistamines, such as Zyrtec (cetirizine) and Benadryl ..., Can You Take Benadryl And Ibuprofen Together? You can generally take Benadryl (diphenhydramine) and ibuprofen together. As they have different mechanisms of action. Benadryl is an antihistamine for allergies. While ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) for pain and inflammation., Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce mild to moderate pain, inflammation, and fever. Ibuprofen works by blocking an enzyme that makes prostaglandin (a hormone-like substance that participates in a variety of body functions), which results in lower levels of prostaglandins in the body., Benadryl (diphenhydramine) is a brand-name, over-the-counter medication that’s classified as an antihistamine. It’s used to help relieve symptoms of hay fever (seasonal allergies), other allergies, and the common cold, as well as itchy skin due to insect bites, hives, and other causes. Benadryl is effective for decreasing itchy skin from hives., You should not take ibuprofen with Eliquis. Taking the combination is known to increase the risk of bleeding episodes. Eliquis is an anticoagulant (i.e. 'blood thinner) used for the prevention of stroke, deep vein thrombosis and pulmonary embolism. It is a good alternative to warfarin (a commonly used blood thinner) as it typically has a …, The best medication for this while on Prozac is Acetaminophen. There are no known interactions between acetaminophen and Prozac (Fluoxetine). There are, however, known drug interactions …, Applies to: clonazepam and Benadryl (diphenhydramine) Using clonazePAM together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., Claritin is known to stay active in your body for a full day, so if you take it in the morning and then take Benadryl at night, there’s a possibility of an interaction. This interaction can result in additive side effects like (4): …, Yes, ibuprofen is safe to take with diphenhydramine (generic for Benadryl). There is no known interaction between the two drugs. In fact, there are several products on the market that contain both drugs in a single pill, such as Advil PM. Below is an image of Advil PM showing it containing both ingredients:, Dr. Ashley Emmert answered. Allergy and Immunology 18 years experience. Yes: Amoxicillin and ibuprofen are safe to take with Benadryl. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help., Dr. Ashley Emmert answered. Allergy and Immunology 18 years experience. Yes: Amoxicillin and ibuprofen are safe to take with Benadryl. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help., Allergy medications from different classes can typically be combined. For example, nasal steroids, like Flonase (fluticasone propionate), and oral decongestants, like Sudafed (pseudoephedrine), are safe to take together. Oral antihistamines, such as diphenhydramine (Benadryl) and cetirizine (Zyrtec), shouldn’t be taken together without a ..., Personal Capital is a useful financial management tool, but is you money safe and secure? Find out what security measures are taken with your data. Personal Capital is a useful fin..., Descriptions. Diphenhydramine and ibuprofen combination is used to relieve trouble sleeping caused by minor aches and pains. It also helps you fall asleep and stay asleep. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used in this combination to relieve inflammation, swelling, and pain., Answer. There is no known drug interaction between Pepcid (famotidine) and Benadryl (diphenhydramine). They are considered safe to take together. Although they both work on histamine receptors, they do so on different ones. Antihistamines like Benadryl block 'H1' receptors, while drugs like Pepcid, Zantac and Tagamet block 'H2' receptors, which ..., The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative ..., According to Drugs.com, Advil and Sudafed are brand names for ibuprofen and pseudoephedrine and may usually be taken together safely. However, there are many potential interactions..., Both Benadryl (diphenhydramine) and clonazepam have CNS (central nervous system) depressant effects and are generally not recommended to be used together. Taking both together can have additive effects which could lead to excess sedation and respiratory depression. The risk is greatly increased if you have a sleep-related breathing …, Yes. Sudafed (pseudoephedrine) is a decongestant, while Benadryl (diphenhydramine) is an antihistamine. "Antihistamines and decongestants work differently and are often combined in cold and ..., Yes, you can safely take acetaminophen and ibuprofen together. And it may surprise you that taking these two medications together actually works better to relieve pain than taking them separately. Studies have shown that ibuprofen (Advil, Motrin) and acetaminophen (Tylenol) together work well to relieve certain types of pain, and with few side ..., Apr 1, 2024 · Diphenhydramine. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Ibuprofen. Studies in women suggest that this medication poses minimal risk to the infant when used ... , A total of 393 drugs are known to interact with ibuprofen . Ibuprofen is in the drug class Nonsteroidal anti-inflammatory drugs . Ibuprofen is used to treat the following conditions: Aseptic Necrosis. Back Pain. Chronic Myofascial Pain. Chronic Pain. Costochondritis. Diffuse Idiopathic Skeletal Hyperostosis. , This deadly TikTok challenge is, unfortunately, back in the news. More than two years after we first heard about the “Benadryl Challenge” on TikTok, it is unfortunately back in the..., Key points. Benadryl and Allegra are both antihistamines, and generally should not be taken together consistently. However, there are times when it may be okay to take both during the course of one day if recommended by your doctor. In most cases, it would not be recommended to take Benadryl ( diphenhydramine) and Allegra ( fexofenadine) together.